This must be the ultimate spoil thread
. When Ash left Pikachu behind in an episode of pokemon season 1, think it was episode 41 or 49 or something. Love Hina made me "cry" a little, Negima! made me cry when Asuna said what she wanted to say in the last episode, some sad Naruto moments, when the third died, when Sasuke was supposed to be dead(lol
), but the sadest must have been the filler episode with Menma. Elfen Lied had some sad moments...