Azumanga Daioh is SOOO funny, and Ouran high school

Yes that is like the funniest anime ever. It;s also my favorite :)

[quote=Kanji_The_Wanderer;73902]A good anime comedy? Watch Genshiken! It is about anime otaku, and their after school club ! :D

I just couldn't said it better myself!^^
I totally agree, Watch Genshiken!:D

Maybe some Happy Lesson, Cromartie High School, Papuwa and Hare+Guu.

Dragon Half is pretty hilarious. Weird, a little pervy, and hilarious.

Killer beating angel dokuro-chan
high school debut has some funny points
full metal alchemist [so funny yt so awesome and sad]

hmm i like pani pony dash, hayate no gotoku, and Wlecome to the N.H.K

Thank you LiberiFatali for mentioning Cromartie and Papuwa! :D

Also, a good dramedy is GTO. :) It has plenty of hilarious, sometimes perversion-filled, antics and scenes, but it knows how to make you cry... o.o

Ouran High School Host Club and Tactics are hilarious!

I'm surprised that no one mentioned Excel Saga. The anime series for that is hilarious. I'm not sure about the manga. I heard that both are pretty different.

Abenobashi Mahou Shoutengai is funny too, and so is Jungle wa Itsumo Hale Nochi Guu. All of these titles have a US release now so they should be pretty easy to find.

Oh, and one of the funniest dubs I've seen would definitely have to be...Samurai Pizza Cats!:p